The correct answer is circled. Can someone explain to me how this is correct? QU

Question

The correct answer is circled. Can someone explain to me how this is correct?

QUESTION What is the minimum number of tRNAs needed for Thr? (codons:ACU,ACC, ACA,ACG) 1. One codon recognized: Anticodon (3') X-Y-C (5') (3)X-Y- A(5') Codon C. 3 2. Two codons recognized: Anticodon (3')X-Y-U(5' (3')X-Y-G (5') D. 4 Codon 3. Three codons recognized: Be sure you can do these without this image You need to know which anticodon nucleotides can recognize which codon nucleotides Anticodon (3') X-Y- (5') Codon

Explanation / Answer

Minimum number of t RNA required for Thr are 2.

As per wobble rule proposed by Francis Crick once first two positions of codon are paired ,exact base pairing of third position is less specific.

wobble rule pairing

codon : anticodon

A : U, C : G, G : C,U, U : A ,G

in case of adenine modified to inosine ( I:A , C, U)

There are 4 codons ACU,ACC,ACA,ACG & 5 anticodonsUGA,UGG,UGU,UGI,UGC in (Thr) synthesis .

For codons ACU,ACC,ACA single tRNA with anticodon UGI is sufficient.

For codon ACG another tRNA with anticodon UGC is needed.

Thus minimum number of tRNA needed for Thr is 2 (UGI & UGC).

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