This is the question I told you about on the Blackboard Announcements page conce
ID: 303155 • Letter: T
Question
This is the question I told you about on the Blackboard Announcements page concerning co-translational insertion and membrane flow. As you organize the outline you are going to use please use the following 4subtitles/categories I provide below. <- Divide your answers into these categories. In a bullet/outline form simply name the component (RNA, protein, membrane etc.) used, in the order used, and where appropriate add a brief descriptor of that component. <- this should take no more than 1 line. Explain what happens at the category AND how the new lipid and protein transit to the next category again using a simple bullet/outline form. The categories are:
A. Before ER
B. At the ER and how it transports to the Golgi
C. At the Golgi and how it transports to the plasma membrane.
D. At the Plasma Membrane
Effectively you are starting with an mRNA in the cytoplasm and processing it all the way through Constitutive and/or Regulative exocytosis. Be sure to include where new lipids are synthesized and how they move with the protein. Don't forget to include the recycling of components when they occur.
Explanation / Answer
This experiment is asking basically how protein are synthesies in eukaryote.
Part-A- in translation, messenger RNA (mrna) is decoded in a ribosome to produce a particular amino acid chain. The polypeptide later folds into a lively protein and plays its features within the cell, ribosome allows deciphering by way of inducing the binding of complementary trna anticodon sequences to mrna codons, trnas deliver precise amino acids which might be chained collectively into a polypeptide because the mrna passes through and is "examine" by way of the ribosome.
Part-B- translation occurs in the cytosol or across the membrane of the ER in a process called co-translational translocation. In co-translational translocation, the entire ribosome/mRNA complex binds to the outer membrane of the rough endoplasmic reticulum and the new protein is synthesized and released into the ER; newly created polypeptide can be stored inside the ER for future vesicle transport and secretion outside the cell, or immediately secreted. the transport of proteins and lipids among the endoplasmic reticulum and golgi apparatus is initiated by way of the collection of secretory cargo from within the lumen of the ER at the end, transport providers are shaped that bud from this membrane and transported to and finally merge with the golgi.
Part-C- Though answer to this is still not clear to scientist that how golgi work for protein synthesis but still some belavie that proteins are sorted into the regulated secretory pathway in the trans golgi community, where they're packaged into specialized secretory vesicles and these secretory vesicles that are large than other transport vesicles, save their contents until unique alerts direct their fusion with the plasma membrane.
Part-D- surfaces of membrane proteins are mosaics, with patches of hydrophobic amino acids wherein the proteins touch lipids in the membrane bilayer of hydrophilic amino acids on the surfaces that make bigger into the water-based cytoplasm.
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