Question 50 (1 point) d What process occurs in the citric acid cycle? a) formati

Question

Question 50 (1 point) d What process occurs in the citric acid cycle? a) formation of a mixed anhydride (acyl phosphate) b) net synthesis of oxaloacetate from two acetyl-CoA molecules c) hydrolysis of two thioester bonds d) All of the answers are correct e) None of the answers is correct Save Question 51 (1 point) During the operation of the malate-aspartate shuttle, what process does NOT a) reduction of oxaloacetate to malate in the cytosol b) transfer of amino groups from glutamate to oxaloacetate in the cytosol c) simultaneous transport of malate and oxaloacetate through an antiport ved

Explanation / Answer

Q. 50. Mixed anhydrides or acyl phosphates are mixed anhydrides of phosphoric acid and fatty acid formed. They are not found at any stage of the Krebs cycle.

During the Krebs cycle oxaloacetate reacts with acetyl coenzyme A and H2O to yield citrate and coenzyme A.

(c) is the correct answer. One thioester bond is hydrolyzed at the beginning of the Krebs cycle when oxaloacetate reacts with Acetyl-CoA. giving products, citrate and CoA-SH. Thioester hydrolysis helps to shift the equilibrium towards product formation.

The other thioester bond is hydrolyzed at the later part of Krebs cycle while succinyl CoA is converted to succinate during substrate level phosphorylation.

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