14. Researchers injected bark scorpion venom in mouse neurons (both a common hou
ID: 301266 • Letter: 1
Question
14. Researchers injected bark scorpion venom in mouse neurons (both a common house mouse and the southern grasshopper mouse) and measured the flow of sodium ions across the cell membrane. Their data is shown below.
Based on these data, what effect do you think the venom is having on the grasshopper mouse?
A. The venom is blocking voltage-gated sodium channels.
B. The venom is opening voltage-gated potassium channels.
C. The venom is blocking voltage-gated potassium channels.
D. The venom is opening voltage-gated sodium channels.
A. The venom is blocking voltage-gated sodium channels.
B. The venom is opening voltage-gated potassium channels.
C. The venom is blocking voltage-gated potassium channels.
D. The venom is opening voltage-gated sodium channels.
Explanation / Answer
A. The venom is blocking voltage-gated sodium channels.
As we see from the plot, increase in the venom concentration is decreasing the sodium channel currents. This indicated the direct effect of the venom on Na+ channel
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