Ancient medical manuscripts were taken from the Winkler Center. Several small dr

Question

Ancient medical manuscripts were taken from the Winkler Center. Several small drops of blood were discovered outside the door entering the room and the display case it was in. The blood was submitted to the Hamilton County Coroner's office for STR loci analysis. The results were compared to the state database and two genotype matches were identified stored in CODIS. 4. FGA D351358 e, Contributor 1 17 16 18 17 ceo 1000 17 a. In this image what do the numbers 18, 20 represent for Contributor 1 at FGA? b. What is the interpretation if two peaks (i.e, 17 in vWA for both contributors) from different sources line up at the same migration speed/distance in capillary electrophoresis? While there are two alleles for most loci what does it mean when only one allele is present? c.

Explanation / Answer

a. The numbers 18, 20 for contributor 1 represent the short tandem repeat sequence present in the FGA locus in the genome.

b. If both contributors have same peaks in a single loci means that contributor 1 & 2 have same alleles at that particular loci.

c. A single allele for a loci means that the gene is expressed in a homozygous condition in the contributor 2.

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