UT EID exon of the CFTR gene that bes between s the length of your PCR product i
ID: 282438 • Letter: U
Question
UT EID exon of the CFTR gene that bes between s the length of your PCR product it each prieP 10nt in length, and the last A. 80bp B 90bp C 100bp D. 110bp 120bp a cles a 11-12. The igure below shows the pedigree of a ftamily in whic C). The disease aliele is rare and has a single origin in the for a SNP locus are shown (A or Mating AC AA d A ating d A d C Mating D A AC CC AC CC AC AA AC AA tt which of the three matings is non-informative (cannot provide information about linkage) assuming that we know the phase of the affected female in Mating 1? A. Mating 1 Mating 2 C. Mating 3 D. None of the above 2 Assuming linkage between the disease gene and the SNP locus, what is the genetic distance etween the two loci? A. 7m.u. 8 10m.u. ?.14 m.u. D. 20 m.u en male insects that are homozygous for several translocations are mated with normal The fertility of these male insects would be reduced The F1 insects would be heterozygous for several translocations. he fertility of the F1 insects would be ceduood femExplanation / Answer
10) Each primer is 10 bp in length. Protein coding exon of CFTR gene is 100 bp in length. There will be two primers. So, the length of PCR product is,
= 100 + 2(10)
= 100 + 20
= 120 bp
(option E).
11) Mating 2 does not produce any information because all the affected parents and offsprings share the common genotype.
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