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I’m not sure how to find out whether it’s Autosomal/X-Y linked but I THINK it’s

ID: 282180 • Letter: I

Question

I’m not sure how to find out whether it’s Autosomal/X-Y linked but I THINK it’s dominant because it’s in both parents (I believe?)
I just need help understanding all three questions/parts! Thanks in advance! Questions 7-8: The figures below are a pedigree analysis of a genetic disorder called small foot, and the corresponding molecular analysis of the small foot gene-associated MstI-RFLP markers of Mary's family. Mary is individual 3 A. The molecular summary of the small foot gene alleles B. A molecular pedigree analysis of the small foot gene 7. Based on the data above, the small foot gene is located on a. Autosome b. X chromosome 8. Based on the data above, the small foot disorder is most likely to be: a. dominant b. recessive 9. What is the probability that Mary will have a child affected by the small foot mutation, if the child's father is a carrier of small foot a. 100% b. 75% c. 50% d. 25%

Explanation / Answer

7. The small foot gene is located on Autosomal.

If it was x-linked or Y linked then the carrier father had to have the disease.

8. The small foot disorder most likely to be recessive.

Because if it was dominant then one individual can never be a carrier and not show the disease. So the gene is recessive.

9. Mary (aa) X Husband (Aa)

aa

diseased

aA

carrier

aa

diseased

aA

carrier

So 50% of the children will be carrier of small foot.

a A a

aa

diseased

aA

carrier

a

aa

diseased

aA

carrier