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lowing characteristics is common to both T-cell receptors and immunoglobulins (B

ID: 281989 • Letter: L

Question

lowing characteristics is common to both T-cell receptors and immunoglobulins (BCR) Select all that apply Somatic recombination of V, D, and J segments is responsible for the diversity of antigen-binding sites. b. Somatic c. Class switching enables a change in effector function e. Carbo hypermutation changes the affinity of antigen-binding sites and contributes to further diversification d. The antigen receptor is composed of two identical heavy chains and two identical light chains. hydrate, lipid and protein antigens are recognized and stimulate a response.

Explanation / Answer

Answer:- a) Somatic recombination of V, D, and J segments is responsible for the diversity of antigen-binding sites.

VDJ recombination is the unique mechanism of genetic recombination that occur during the early stages of T and B cell maturation. It involves somatic recombination which results in high diversity of antigen-binding sites of antibodies/immunoglobulins and T cell receptors found on B cells and T cells respectively.

So correct answer is option (a).