1. Match the catalytic receptor/pathway with its appropriate description listed

Question

1. Match the catalytic receptor/pathway with its appropriate description listed below. Janus kinase P13K Src STAT a. A series of Ser/Tbr kinases are phosphorylated leading to the phosphorylation b. Tvr residues of the SH2 domain are phosphorylated to form dimers that ?. PIP2 is phosphorylated to PP, which recruits Akt. Akt, in turn, phosphorylates d. SH1 catalytic domain of this nonreseptor tyrosine kinase phosphorylates Tyc e. Phosphorylation of Tyc residues of cytosolic receptor tails allows for binding of of transcription factors translocate to the nucleus to activation transcription factors Bad, preventing apoptosis from occurring residues of membrane.bound receptors STAT which also gets phosphorylated

Explanation / Answer

Janus Kinase Tyr residues of the SH2 domain are phosphorylated to form dimers that translocates to the nucleus to activation transcription factors.

PI3K PIP2 is phosphorylated to PIP3 which recruits Akt. Akt, in turn phosphorylates Bad, preventing apoptosis from occurring. Ras The series of Ser/ Thr kinases are phosphorylated leading to the phosphorylation of transcription factors

Src SH1 catalytic domain of this nonreceptor tyrosine kinase phosphorylates Tyr residues of membrane-bound receptors

STAT phosphorylation of Tyr residues of cytosolic receptor tails allows for binding of STAT which also gets phosphorylated.

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