Malaraxia Inc. has developed an antimalarial drug that they hope acts as “SERCAP

Question

Malaraxia Inc. has developed an antimalarial drug that they hope acts as “SERCAP” – or Single-Exposure Radical Cure and Prophylaxis. To assess its efficacy in curing patients and preventing future infections, parasites from the patient prior to treatment are analyzed by molecular barcoding. They are then also barcoded during any additional infections in the next three years.

1. Patient A presents with an initial malaria infection in June and is immediately treated. They then return to the hospital in July with confirmed malaria, and their parasites are barcoded again. The genotypes observed in June and July are shown below.

Explanation / Answer

1. C Drug resistance

Due to mutation the gene coding changes and become resistance.

2. B. Reinfection

All the genes are sames but infection reoccured.

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