Viral Genetics Get the flu shot, not the flu luenza. It\'s there in every unit,
ID: 278440 • Letter: V
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Viral Genetics Get the flu shot, not the flu luenza. It's there in every unit, every news channel and every season! The CDC reports a ral of 171 pediatric deaths from the 2017-2018 flu Why do we need to create and administer a flu vaccine every year? Is it due to antigenic drift or antigenic shift? (1 point) 1. B/c the nd ?.rus keeps changny Dac to antigeric drite 2. Explain how this form of genetic change occurs to influenza within a host. (Hint: is it due to reassortment between two Influenza viruses or mutations, etc). Please be thorough in your response. You may draw it out if it helps. (2 points) 3. Recently, flu vaccines for 2017-2018 included protection against H3N2. What does H3 and N2 represent? Please spell them out for full credit.You may need to refer back to unit 1. (1 point). H-hen aselath -11, e are le saloyrd N- newramhdove Hlere are suspe 4. Research why the flu is potentially fatal. Why did so many children unfortunately die ded/ didnt 80%aale kids ger tle Plu shet uno this season? (1 point).Explanation / Answer
1). The influenza virus can infect various animal species, i.e. humans, pigs, and birds. So, the viruses from these animals can infect the same cell. If this happens, the RNA (ribonucleic acid) segments of the virus uncoat and get mixed in the cytosol, which will re-sort and form a new genome for the influenza virus with a new hemagglutinin gene. This mixing process of RNA segments is called, “antigenic shift.” This large antigenic shifts generally occurs for every 10-15 years.
We need to take influenza vaccine every year because the influenza viruses adapt to the developed immunity and evolve new virions that are not sensitive to the previous vaccines. So, influenza vaccines are released every year according to the newly evolved strains.
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