3. (4 points) You have a patient that has trisomy 13 syndrome (Patau\'s syndrome

Q: 3. (4 points) You have a patient that has trisomy 13 syndrome (Patau's syndrome

3 A) In meiosis first and second stage nondisjunction occur allowing the gamete to have more than one copy of chromosome 13 in patau' s syndrome B) In normal meiosis, 4 gamates are produced. In each gamete, one copy of chromosome 13 is present. C) If nondisjunction occurs, 2 gametes will have more than one copy of chromosome 13 at the end of meiosis. 2 gametes will have n-1 genotype.

ID: 278244 • Letter: 3

Question

3. (4 points) You have a patient that has trisomy 13 syndrome (Patau's syndrome). Please answer the following questions a. (1 point) During which specific stages of meiosis could non-disjunction occur that would allow a gamete to have more than one copy of chromosome 13? b. (1 point) In normal meiosis (no non-disjunction), how many gametes are produced, and how many copies of chromosome 13 are present in each? c. (1 point) For each stage you stated in part (a), when non-disjunction occurred how many gametes ended with more than one copy of chromosome 13 at the end of meiosis? How many ended with 0 copies?

Explanation / Answer

A) In meiosis first and second stage nondisjunction occur allowing the gamete to have more than one copy of chromosome 13 in patau' s syndrome

B) In normal meiosis, 4 gamates are produced. In each gamete, one copy of chromosome 13 is present.

C) If nondisjunction occurs, 2 gametes will have more than one copy of chromosome 13 at the end of meiosis.

2 gametes will have n-1 genotype.

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3. (4 points) You have a patient that has trisomy 13 syndrome (Patau\'s syndrome

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