Orcanelles and Iliness Activity ackground and Instructions: You are part of a re

Question

Orcanelles and Iliness Activity ackground and Instructions: You are part of a research team that specializes in diagnosing disorders associated with malfunctioning cellular organelles and structures. For each case, use the lab result data provided to figure out which organelle is not working properly Case number 1 Patient History: Seven year-old male suffering from fatigue, muscle weakness, loss of coordination Physical Examination: Muscle loss & deformity, awkward gait, difficulty breathing Laboratory Results o Cells have abnormal shape o Cell division is abnorma o Impaired intracellular movement of materials Diagnosis o Malfunctioning Organelle Case number 2 Patient History: 55 year-old female with recent onset of fatigue, headaches, diarrhea, dizziness vomiting and weight loss Physical Examination: Partial limb paralysis, hyperkeratosis (increased pigmentation) of skin Laboratory Results o Low levels of ATP production o Abnormal levels of cell death which appears to be due to lack of energy to maintain homeostasis Diagnosis o Malfunctioning Organelle Case number 3 Patient History: 2-day old male with low birth-weight (4pds. 5 ounces), difficulty suckling/swallowing, seizures, and gastrointestinal bleeding Physical Examination: enlarged liver, low muscle tone/inability to move, and jaundiced skin Laboratory Results o o Diagnosis High levels of hydrogen peroxide in cells High levels of fats and amino acids in cells o Malfunctioning Organelle Case number 4 Patient History: 42 year-old male with recent lethargy, significant weight gain Physical Examination: Enlarged liver and muscle weakness Laboratory Results o o Diagnosis High levels of fat in liver-abnormal fat metabolism Abnormal cell calcium balance o Malfunctioning Organelle:_ dapted from Organelles and Ilnesses C2011 McGraw-Hill Higher Education

Explanation / Answer

Case 1- organelle will be centriole because it is responsible for cell division and formation of spindle.

Case2- mitochondria... It is power houHo of the cell. It maintain energy production in the cell.

Case 3- peroxisomes

They regulate the amount of hydrogen peroxide in the cell.

Case 4- endoplasmic reticulum

It is involved in synthesis of fat and storage of calcium.

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