7. The figure below shows a signal transduction pathway involving two proteins f

Question

7. The figure below shows a signal transduction pathway involving two proteins found in the cytoplasm -JAK and STAT. Based on this figure, what are the roles of JAK and STAT in this pathway? Outside of cetokine Inside of cel Dimerization Nuclous mRNA JAK is a protein kinase and STAT is a G protein. JAK is a G protein and STAT is adenylyl cyclase. JAK is a G protein and STAT is a transcription factor. JAK is a transcription factor and STAT is a GTPase. JAK is a protein kinase and STAT is a transcription factor.

Explanation / Answer

JAK is a protein kinase ans STAT is a transcription factor.here as the ligand bind to the receptor JAK being a kinase transfer a phosphate group to STAT.Due to which STAT dimerise and take a entry into the nucleus where it binds to DNA as a transcription factor.

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