Academic Integrity: tutoring, explanations, and feedback — we don’t complete graded work or submit on a student’s behalf.

1. Immunoglubulins _______. a Bind antigens with a 1:1 stoichiometry b Are produ

ID: 276204 • Letter: 1

Question

1. Immunoglubulins _______.

a Bind antigens with a 1:1 stoichiometry

b Are produced and secreted by macrophages

c Bind tightly to their antigens

d Form four classes of antibodies

2. Which description is associated with immunoglobulin G?

a Most abundant immunoglobulin

b Consists of one heavy and one light chain

c Consists of two Fc fragments and two Fab fragments

d Important in allergic response

3. The molecular structure for which an individual antibody or T-cell receptor is specific is known as _____.

a An epitope

b An immunoglobulin fold

c Its target

d An immune response

4. Which of the following statements is true about using the Hill equation?

a Log Kd must be concerted to log P50

b It is possible to observe negative cooperativity

c It will never be 1 for a multisubunit protein

d It cannot be applied to noncooperative binding

5. Regarding the models of cooperativity, _________.

a The concerted model and the sequential model are mutually exclusive

b The concerted model is based on the T state and the sequential on the R state

c T state is low affinity and R state is high affinity

d These models, strictly speaking, only apply to tetramers.

Explanation / Answer

1. a. Bind antigens with a 1:1 stoichiometry

2. a. Most abundant immunoglobulin

3. a. An epitope

4. b. It is possible to observe negative cooperativity

5. c. T state is low affinity and R state is high affinity