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7- Genomic rearrangement in B cells occurs: during clonal selection after antige

ID: 275478 • Letter: 7

Question

7- Genomic rearrangement in B cells occurs:

               during clonal selection after antigen binding.

               in the bone marrow when B cells divide and produce daughter B cells.

               after clonal selection when antibodies are required for immune response.

               in the gamete-producing cells of an individual.

9- Sometimes an organ can be replaced by moving it from one part of the body to another. This can be done, for example, to replace damaged skin or joints. In these cases:

               antigens would be generated against the transplanted organ.

               antibodies would be generated against the transplanted organ.

               immunosuppressant drugs would be required to prevent transplant rejection.

               rejection of the transplanted organ would not be expected.

               rejection of the transplanted organ would still be expected.

10- A woman goes to the doctor and is diagnosed with rheumatoid arthritis. What factors led to her developing this disease? (Select all that apply.)

               Some of her T cells were not negatively selected.

               Some of her T cells are recognizing and responding to herself antigens.

               Some of her T cells were not positively selected.

               Some of her T cells are not recognizing and associating with her MHC proteins.

11- Cells with class I MHC proteins that contain a foreign antigen will be destroyed after:      

               releasing histamine.

               being bound by helper T cells.

               stimulating the MAC.

               being bound by cytotoxic T cells.

12- Virus-infected cells are detected and destroyed by which cell-mediated immune response?

               macrophages

               cytotoxic T cells

               helper T cells

               B cells

13- Which of the following is required to activate a helper T cell, which in turn can stimulate antibody production by B cells?

               an antigen

               a major histocompatibility complex

               an antigen and a major histocompatibility complex protein

               an antibody and a major histocompatibility complex protein

               an antibody

14- The secretion of cytokines is a function of _____ cells.

               plasma

               cytotoxic T

               killer T

               helper T

Explanation / Answer

7) after clonal selection when antibodies are required for immune response.

9) rejection of the transplanted organ would not be expected.

10)

11)being bound by helper T cells.

12)helper T cells

13)an antigen and a major histocompatibility complex protein

14) T helper cells

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