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1) (15 point question) Panel A shows the initial crosses and representative chro

ID: 275443 • Letter: 1

Question

1) (15 point question) Panel A shows the initial crosses and representative chromosomes of animals in a QTL mapping project. The black regions represent chromosome material from the largest purebred line and the white regions represent the other pure bred line used in the experiment. Panels B, C, D and E show the karyotypes representative of the smallest and darkest animals from populations of mice that were created for QTL mapping.

E) (3 points) The researchers document the full size for all the mice in the F2 population, but also the F1 and parental populations. Even in the inbred lines the sizes are variable (see the table for the size variance of each mouse population). What is the broad sense heritability of the size trait based on these data in the table below. Show your calculations.

Pure line A Pure line B RR RR BR

Explanation / Answer

In pure line A and pure line B variance is only due to environment factors not due to genetics factors and here in f1 generation varience is 22.

Total varience = varience due to environment +varience due to genetics

V= Ve+ Vg and here vg is 0 whearese in F2 varience is due to both genetic factor and environment factor

F2= vg + ve

26=vg+22

Vg= 26-22=4 and broad sense heritibality formula is vg/vg+ve  

So 4/26=0.15