12. All protein coding genes are transcribed by RNA polymerase I A TRUE B. FALSE
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Question
12. All protein coding genes are transcribed by RNA polymerase I A TRUE B. FALSE 13.Compared to the human genome, the genome of yeast typically has A) more repetitive DNA. B) longer genes C) more introns D) longer chromosomes. E) a higher fraction of coding DNA 14.The chromatin remodeling complexes play an important role in chromatin regulation in the nucleus. They... A) can slide nucleosomes on DNA B) have ATPase activity C) interact with histone chaperones D) can remove or exchange core histone subunits. E) All of the above. 15.The acetylation of lysines on the histone tails A) loosens the chromatin structure because it adds positive charges to the histone. B) recruits the heterochromatin protein HP1, resulting in the establishment of heterochromatin C) can be performed on methylated lysines only after they are first demethylated D) is sufficient for the formation of an open chromatin structure E) is a covalent modification and is thus irreversibleExplanation / Answer
12. B, False
Protein coding genes are transcribed by RNA polymerase II
13. E
Much of the genome of yeast is dedicated for protein coding. It does not contain repetitive elements.
14. E
Nucleosome remodelling is induced by an energy dependent process that weakens the contact between the nucleosome and the DNA. It involves cis-trans displacement of nucleosomes.
15. D
Acetylation removes negative charge from lysines and thus reduce affinity of histones with DNA. This opens the chromatin.It is performed by histone acetyl transferases (HATs).
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