Which statement regarding regulation of acetyl-CoA carboxylase is false? O O O O
ID: 275065 • Letter: W
Question
Which statement regarding regulation of acetyl-CoA carboxylase is false? O O O O Phosphorylation activates acetyl-CoA carboxylase. Active acetyl-CoA carboxylase polymerizes into long filaments. It is the rate-limiting step of fatty acid biosynthesis. Citrate allosterically activates acetyl-CoA carboxylase. Long chain and unsaturated fatty acids are O elongated in mitochondria and desaturated in peroxisomes all dietary essential fatty acids O generally produced by enzyme systems found in mitochondria and the endoplasmic reticulunm O all produced from linoleate Which statement does not describe a feature of the eicosanoids? PGH2 synthase, which is irreversibly inhibited by aspirin, catalyzes conversion of arachidonate to prostaglandin H2 The thromboxanes are all made from ?-linolenate, and the leukotrienes are all made O O from arachidonate. They are ultimately derived from dietary linoleate. Some eicosanoids are produced from docosahexaenoic acid.Explanation / Answer
1. Option 1st is the correct answer. Phosphorylation of acetyl coA carboxylase occurs by AMP regulated protein kinase which results into inactivation of acetyl coA carboxylase. Protein phosphatase remove the phosphate group from acetyl coA carboxylase and makes it active.
2. Option 3rd is correct. Fatty acid synthesis involves many enzyme. The two important enzyme are fatty acid elongase and fatty acid desaturase found in mitochondria and endoplasmic reticulum respectively.
3. Option 2nd is the coreect answer. Thromboxanes and leukotrienes all made from arachidonate.
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