10. The pathway involves the assembly of a nucleotide from PRPP and a nucleobase
ID: 274063 • Letter: 1
Question
10. The pathway involves the assembly of a nucleotide from PRPP and a nucleobase 11. In the de novo pyrimidine biosynthesis pathway, the initial nucleotide formed is 12 This pype oftopoisomerase can change the linking number(noumber of supercoils) of supercoiled DNA by 2 AL- 2): 13. UV light can cause damage to DNA by forming 14. The creation of a(n) site is required in the first step of the Base Excision Repair (BER) pathway. 15 are intermediates in recombination pathways and are composed of four polynucleotide chains in a cross-like structure. 16. The low-fidelitypolymerases are employed in the SOS response 17. A(n) is a sequence of DNA that codes for the specific enzymes necessary to insert itself into the recipient DNA. 18. In order to determine where transcription begins, RNA polymerase must specifically bind to the region of the DNA templateExplanation / Answer
10) salvage pathway
Free purine bases derived from turn over of nucleotides or from the diet can be attached to PRPP to form purine nucleoside monophosphate
11) Uridine triphosphate (UTP)
Denovo synthesis of UMP is completed in 6 steps from simple precursors. UMP acts as a precursor for CTP and dTTP
12) Type IIA and IIB topoisomerases
Type II topoisomerases cuts both strands of one DNA double helix, passes another unbroken DNA helix through it and then religates the cut strands.
13) Thymine dimer
The energy of UV light alter Thymine chemical bonding causing a dimer formation in DNA.
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