39. Signal transduction pathways that require the synthesis of new considered fa

Question

39. Signal transduction pathways that require the synthesis of new considered fast pathways proteins are generally A. True B. False 40. A synthesized protein with the following configuration will have its N-terminus and C-terminus in which configuration? Signal- protein -stop- protein A. N-terminus ER, C-terminus->Cytoplasm B. N-terminus- Cytoplasm, C-terminus- ER C. N-terminus- ER, C-terminus ER D. N-terminus Cytoplasm, C-terminus Cytoplasm 41. A scientist has just designed a new drug to treat cancer. She realises that it takes onl She correctly concludes that the drug acts by ly a few mins for the drug to take effect after binding to its receptor on the cell surface. A. Inhibiting/affecting already synthesized proteins via post-translational modifications B. Increasing DNA activity C. Modifying ribosomal activation D. Reversing the harmful mutagenesis effects that happened to the cell

Explanation / Answer

39. False Signalling pathways that require synthesis of new proteins are slow as compared to pathways that involves post-translational modification of proteins.

40. A. newly synthesised proteins have a N-terminal signal peptide, that directs it to the endoplasmic reticulum. The N-terminal enters the ER lumen as the protein is still being synthesised.

41. A. drugs that acts through second messengers and post-translationally modifies proteins acts in a short time duration (usually minutes).

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