1. Catalytic RNAs are broadly separated into two classes based on their size and

Question

1. Catalytic RNAs are broadly separated into two classes based on their size and reaction mechanisms. The large catalytic RNAs (consist of RNase P, and the group I and group II introns) and small catalytic RNAs (include the hammerhead, the hairpin (or paperclip), hepatitis delta and VS RNA). Differentiate the classes based on its structure and reaction mechanism. Note: If needed, illustrate the reaction mechanism 2. What is an abzyme? How is it different from an enzyme and an antibody? What are its properties? Give specific examples of abzymes 3. How is abzymes produced? Give specific example of application of abzyme technology

Explanation / Answer

2. Abzyme is catalytic antibody(monoclonal antibody+enzyme),actioned against the haptens.

Unlike other enzyme and antibody abzymes in the form of antibodies can produce stable transition state analog,means resembles catalytic activity with antibiotic activity.(properties & difference from enzyme & antibody)

Abzyme treated against AIDS

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