The biosynthesis of the amino acid serine occurs through a series of reactions.
ID: 271082 • Letter: T
Question
The biosynthesis of the amino acid serine occurs through a series of reactions. 3-phosphoglycerate dehydrogenase (PHGDH), the enzymatic protein that catalyzes the beginning steps in the series, was purified from bacterial cells. The rate of the reaction catalyzed by PHGDH was measured under varying concentrations of serine, with the results summarized in the table.
The data show that serine _____ PHGDH. This could possibly occur by serine binding to PHGDH, resulting in a change in the protein’s _____ structure.
The biosynthesis of the amino acid serine occurs through a series of reactions. 3-phosphoglycerate dehydrogenase (PHGDH), the enzymatic protein that catalyzes the beginning steps in the series, was purified from bacterial cells. The rate of the reaction catalyzed by PHGDH was measured under varying concentrations of serine, with the results summarized in the table.
The data show that serine _____ PHGDH. This could possibly occur by serine binding to PHGDH, resulting in a change in the protein’s _____ structure.
inhibits; primary. activates; primary. inhibits; tertiary. activates; tertiary. activates; secondary.Explanation / Answer
ANSWER
The data show that serine inhibits PHGDH. This could possibly occur by serine binding to PHGDH, resulting in a change in the protein’s tertiary structure.
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