10. Glutathione does all of the following EXCEPT: A. participate in the transpor
ID: 269803 • Letter: 1
Question
10. Glutathione does all of the following EXCEPT: A. participate in the transport of amino acids across some cell membranes. scavenge peroxides and free radicals. C. form sulfur conjugates for detoxication of compounds. D. convert hemoglobin to methemoglobin. E. act as a cofactor for some enzymes. 1. Which of the following enzymes would show the greatest increase in serum activity in viral hepatitis? A. creatine kinase B. alkaline phosphatase C. alanine aminotransferase D. 5' nucleotidase E. acid phosphatase ood 12 -Which of these risks are likely to occur in a pregnancy in which the mother's bl phenylalanine is poorly controlled? a) spontaneous abortion b) mental retardation in the infant c) microcephaly in the infant d) congenital heart disease in the infant e) all of the above 13. Histidine: A. unlike most amino acids, is not converted to an a-keto acid when the amino group is removed. B. is a contributor to the tetrahydrofolate one-carbon pool. C. decarboxylation produces a physiologically active amine. D. forms a peptide with beta-alanine. E. all of the above are correct 14. What is the name of the cofactor for AST, ALT, or any other transamination reaction? A NAD B Acetyl CoA C Pyridoxal phosphate (PLP) D FADH2 E NADPHExplanation / Answer
10. Glutathione is anantioxidant present in cells. It performs several important functionsin cellular metabolism. These include transport of amino acids across plasma mmebrane, antioxidant activity eliminating the free radicals and formation of sulfur conjugates dring detoxification of compounds. It also converts hemoglobin into methemoglobin. It does not act as a coenzyme. Therefore, option E is correct.
11. Liver enzymes have major roles in detoxification and waster removasl. In acute liver infections such as viral hepatitis, the liver enzymes increase in concentration in serum. The diagnosis of viral hepatitis can be done measuring serum concentrations of liver enzyme alanine aminotranferase. Option C is correct.
12. Excess levels of phenylalanine in blood of pregnant woman is turn out to be teratogenic showing adverse effects on fetus. The maternal phenylketonuria (PKU) due to high phenylalanine levels may result in spontaneous abortion, intrauterine mental retardation, congenital heart disease and microencephaly etc. Option e is correct.
13. Histidine is an alpha- amino acid that contains positive chrage at physiological pH. Histidine is decaroxylated to form physiologically active histamine compound that participates in inflammation reaction. The degradation of histidine results in formatioin of tetrahydrofolate. deamination of histidine results in formation of amino acids proline and arginine. Carnosine is dipeptide formed by histidine with beta- alanine. option E is correct.
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.