RNA is synthesized by which RNA polymerase: o) None of the above 40. Study the n
ID: 269664 • Letter: R
Question
RNA is synthesized by which RNA polymerase: o) None of the above 40. Study the nucleotide sequences of wild type and it's mutant gene below Protein DNA Met Pro-Lyn-Pro -Lys Met ATG CCCAAA CCCAAA ATO DNA ATG CCC GAA COCAA ATG This mutation can best be called A) Non-sense B) Silent C) Frameshift D) Mis-sense E) All of the above 41. The following statement is true about carcinogenesis A) Proto-oncogene product has mutation B) Tumor suppressor gene product must lose activity C) Tumor suppressor gene product must have an increased activity DIA, B and C E) A and B 42. The mechanism by which phosphorylation regulates a protein function is called as A) Feedback inhibition B) Post-translational modification C) Post-transcriptional modification D) Allosteric inhibition 43. CDKs form complex with to control cell cycle. A) Histone acetyl transferase B) Histone methyltransferase C) Cyclins D) Transcription factorsExplanation / Answer
39. mRNA is synthesized by RNA polymerase II
40. A non-sense mutation is the mutation which is a codon corresponding to a specific amino-acid is coverted to stop codon. A silent mutation is the mutation in the base which does not change the amino acid to which the codon was coding. A frameshift mutation is the mutation caused by the deletion or addition of the base which then ultimately changes the sequence of the amino acid chain to which the DNA was coding. A mis-sense mutation is a point mutation in which one base is changed to another causing the change in the amino acid to which the codon was coding. So according to the question this mutation is a MIS-SENSE mutation as it does a point mutation at position 7 causing the amino acid to change from glutamic acid to lysine.
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