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12- Which of the following would be characterized as an autocrine signal? contac

ID: 269529 • Letter: 1

Question

12- Which of the following would be characterized as an autocrine signal? contact b. endocrine c. self-responding d. distal neighbors e. both b and d 13-In which of the following is the ligand not a secreted molecule? a. Autocrine signaling. b. Paracrine signaling. c. Endocrine signaling. d. Neuronal signaling. e. Contact-dependent signaling. 14- In which of the following is the ligand secreted in the bloodstrcam? a. Autocrine signaling. b. Paracrine signaling. c. Endocrine signaling. d. Neuronal signaling. e. Contact-dependent signaling. 15- Which of the following is NOT an intracellular receptor? a. Glucagon receptor (a type of G protein-coupled receptor [GPCR b. Testosterone receptor. c. Retinoic acid receptor. d. Nitrite oxide receptor. e. a and d. 16- Which of the following is not a nuclear receptor? a. Glucagon receptor b. Testosterone receptor. c. Retinoic acid receptor. d. Nitrite oxide receptor. e. a and d. 17- Which of the following component of the G-proteins binds GTP? a. The a subunit. b. The B subunit. c, The ? subunit. d. The ?? complex. e. The By complex. 18-One of the targets of the complex is a. a plasma membrane calcium channel. b. a plasma membrane potassium channel. c. an ER membrane calcium channel. d. an ER membrane potassium channel. e. None of the above. 19- Which of the following is a FALSE statement about GPCR signaling? a. The ligand-bound receptor recruits the trimericG protein complex b. The activated a-subunit is GTP-bound. The Py complex can open an ion channel. d. In order to be inactivated, the a-subunit must hydrolyze GTP into GDP and Pi. e. All of the above are true statements. c.

Explanation / Answer

12. Self responding is the characteristic of autocrine signal.

13. Contact dependent signalling not secrets ligand.

14. Endocrine secrets ligand in blood stream.

15. Testosterone receptor and retinoic acid receptor are not intracellular receptor.

16. Glucagon receptor & nitric oxide receptor are not nuclear receptor.

17. Alpha subunit of the G protein binds GTP.

18. A plasma membrane calcium channel.

19. All the informations are true.