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An RFLP is a DNA probe variation in size of a DNA segment when cut by a restrict

ID: 267916 • Letter: A

Question

An RFLP is a

DNA probe

variation in size of a DNA segment when cut by a restriction enzyme

type of restriction enzyme

type of copy number variant

forensic DNA

The study of the factors that control or contribute to a disease is called:

Epidemiology

Cardiology

Oncology

none of the above

Cancer terminology

An occurrence when a section of a chromosome relocates itself to a non-homologous chromosome is called a/an:

Inversion mutation

Translocation mutation

Transformation mutation

Duplication mutation

Mutations

a group formed to evaluate moral and ethical concerns arising from the Human Genome Project is:

ELSI

NIES

MORA

SILES

Genetic engineering

Patterns made by restriction fragments in an agarose gel creates a/an:

Southern Blot

Northern Blot

VNTR

DNA fingerprint

Genetic engineering

Mutations and polymorphisms both involve changes in DNA, but polymorphisms are more common because:

mutations are always lethal.

more people have them.

mutations refer to a real situation, whereas polymorphisms are more hypothetical and used by biologists to explain genetic changes in an entire population.

they affect phenotype less severely and allow individuals to reproduce and transmit them to future generations.

The promoter of a gene is the part of a gene that marks the:  

start point of translation

start point of a gene

end point of transcription

end point of translation

Histone proteins:

control gene expression through chemical interactions that expose parts of the DNA to translation factors.

bind to tRNAs to prevent translation

control gene expression through chemical interactions that expose parts of the DNA to transcription factors.

bind to mRNAs to prevent translation

Explanation / Answer

1) An RFLP is a copy number variant.

Restriction Fragment Length Polymorphism (RFLP) is a difference in homologous DNA sequences that can be detected by the presence of fragments of different lengths after digestion of the DNA samples in question with specific restriction endonucleases.

2) The study of the factors that control or contribute to a disease is called: Epidemiology

Epidemiology is the branch of medicine which deals with the incidence, distribution, and possible control of diseases and other factors relating to health. It is the study and analysis of the distribution and determinants of health and diseased conditions in defined populations.

3) An occurrence when a section of a chromosome relocates itself to a non-homologous chromosome is called a/an: Translocation mutation

Translocation is an exchange of chromosomal segments or whole arms between two (or more, in rare cases of complex chromosomal rearrangement [CCR]) different chromosomes or non-homologous chromosomes.

4) ELSI is a group formed to evaluate moral and ethical concerns arising from the Human Genome Project.

The Ethical, Legal, and Social Implications (ELSI) program was founded in 1990 as an integral part of the Human Genome Project. The mission of the ELSI program was to identify and address issues raised by genomic research that would affect individuals, families, and society.

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