1. The role of amino transferase enzymes in amino acid metabolism is to convert:
ID: 267805 • Letter: 1
Question
1. The role of amino transferase enzymes in amino acid metabolism is to convert: A), ammonia to amino acids C). amino acids to E). Both B and C. keto acids to amino acids keto acids D). Both A and B 2. An infant who appeared normal at birth began to develop lethargy, hypothermia and apnea at 36 hours. The infant was found to have high levels of blood ammonium and low levels of blood urea nitrogen (BUN). The infant was treated with arginine supplements. What enzyme deficiency did this infant most likely have? A). Glutamine synthase D). Argininosuccinate lyase C). Arginine synthase B). Arginase E). Argininosuccinate synthase 3. Via enzymes of the urea cycle, aspartate A). provides nitrogen for the synthesis of arginine. B). provides the carbon found in urea. C). is converted to malate. D). is converted to oxaloacetate. E). combines with ornithine to produce citrulline. 4. Liver damage and liver disease cause jaundice, a build-up of bilirubin in the blood Which of the following correctly describes the normal metabolism of bilirubin A). Bilirubin is produced by the breakdown of heme, is transported to and conjugated in the liver, and is then secreted with other bile components into the small intestine. B). Bilirubin is a by-product of heme synthesis that is conjugated with glucuronic acid in the liver. C). Bilirubin is produced when heme metabolism is blocked due to liver dysfunction. D). Bilirubin is a small protein that gets glycosylated in the liver before it can be disposed of. E). Bilirubin is produced by the breakdown of heme and is transported to the liver where it is further metabolized to TCA cycle intermediates.Explanation / Answer
1 - both A and B
AminoTransferases are enzymes that catalyse a transamination reaction between an amino acid and a keto acid.
2) Argginosuccinate lyase
3) Provides nitrogen for the synthesis of arginine
4)B - Bile rubin is a by product of heme synthesis that is conjugated with glucuronic acid in the liver.
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