There are several efforts underway to identify human genetic polymorphisms that
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There are several efforts underway to identify human genetic polymorphisms that correlate with multifactorial disease such as cancer, heart disease and diabetes. What would be the uses of such information? What concerns do you think are being raised about this kind of genetic testing? There are several efforts underway to identify human genetic polymorphisms that correlate with multifactorial disease such as cancer, heart disease and diabetes. What would be the uses of such information? What concerns do you think are being raised about this kind of genetic testing?Explanation / Answer
When within a population, more than one alleles are situated in a gene locus, then it is known as polymorphic gene. Or in principle a gene can exists in several different form. The polymorphic expression of gene is responsible for deformed protein formation and are cause of several diseases like cancer, diabetes.
A genetic polymorphism analysis for individual can be useful for several purposes like drug development. As gene polymorphism is one of the main reason behind the difference of how individuals are responding to a partcular drug, In addition, clinial trails of human for particular medicine, or their toxicity testing can also be improved with knowledge of individuals genotype.
However, there are few concerns in relation to such genetic testing. Individuals with a preknowledge about some disease which might not be curable might get associated with psycological consequences. Secondly if an individual get identified with several polymorphism in comparison to a healthy individual insurance companies and emplyers may discremenate based on their genetic model. The screening assay also can have an impact on reproductive bahaviour of an individual.
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