Question 9 What is the function of inverted chromosome segments included in bala

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Question 9 What is the function of inverted chromosome segments included in balancer chromosomes? New recessive mutations covered by 1 inversions may be identified as a result of pseudodominance Inversions tend to stimulate recombination 2 that can expedite mapping of new mutations Strains that are heterozygous for inversions display increased fertility They prevent the recovery of recombinants so that chromosome segments may be transmitted intact for multiple generations 4) They promote recombination so that chromosome segments are broken up before being passed on to future generations

Explanation / Answer

Option second (2) is correct. Balancer chromosomes are produced by multiple, nested chromosomal inversions which suppress the synapsis (crossing over) between the homologous chromosomes. Progeny having chromosomes that are the products of recombination between balancer and normal chromosomes (without inversion, homologous chromosome) do not alive. If crossing over between a balancer chromosome and the balancer's homolog does occur during meiosis each chromatid ends up lacking some genes and carrying two copies of other genes while Recombination in inverted regions leads to dicentric or acentric chromosomes (chromosomes with two centromeres or no centromere).

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