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Examples of biological barriers include: Oxidases Dehydrogenases Efflux pumps No

ID: 265083 • Letter: E

Question

Examples of biological barriers include:

Oxidases

Dehydrogenases

Efflux pumps

None of the above

The following drugs do not react with MRP1:

Digoxin

Erythromycin

hydrocortisone

testosterone

MRP2 is ubiquitous

True

False

Chemical barriers to drug delivery can include all the following except:

size

structure

solubility

bioactivity

Define a pro-drug.

Release of an oil-based injectable solution is based on (multiple answers):

drug partitioning

bioconversion

dissolution in the tissue

fusion with the cell

All of the following can be delivered as parenteral biodegradable microspheres with the exception of:

paclitaxel

atrigel

rapamycin

aripiprazole

What triggers insulin release from the Technosphere carrier particle?

Enzymatic cleavage

Oxidative stress

pH

None of the above

The following vaccines can be delivered via nasal aerosol:

Polio

Tuberculosis

Chicken pox

Whooping cough

Paclitaxel can be delivered as a polymeric nanoparticle called:

Caelyx

DepoCyt

Genexol

Abraxane

List and describe 3 ways to trigger drug delivery from a “Smart” drug delivery system.

Particles ? 5?m will be deposited ________ during inhalation delivery

Cilia

Trachea

Alveoli

Bronchioles

List and compare the 3 principle pulmonary aerosol devices.

What are the 3 general types of stem cells?

Explanation / Answer

Examples of biological barriers include: Oxidases Dehydrogenases Efflux pumps No

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