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The RFLP marker (alleles R1 or R2) is linked to the A locus (alleles A or a). Do

ID: 265058 • Letter: T

Question

The RFLP marker (alleles R1 or R2) is linked to the A locus (alleles A or a). Dominant A causes the phenotype of hairy toes. Pedigree analysis of 3 generations of a family is shown, where individuals displaying the dominant phenotype of hairy toes are shaded. Southern blot analysis was alsa done with a probe to identify the RFLP marker present in each individual a. Draw and label the arrangement of alleles of the female and male in generation II. b. The male and female in generation Il have ten children. Which child or children are recombinants? For each recombinant child, draw and label their arrangement of alleles. c. Calculate a LOD score for linkage of these two genes and interpret you result. a.

Explanation / Answer

The RFLP marker (alleles R1 or R2) is linked to the A locus (alleles A or a). Do

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