I ONLY need help with the question asked at the bottom. Thank you. Students of b

Question

I ONLY need help with the question asked at the bottom. Thank you.

Students of biochemistry are frequently distressed by “Svedberg arithmetic,” that is, for instance, by the fact that the 30S and 50S ribosomal subunits form a 70S particle rather than an 80S particle. Why don’t the numbers add up to 80?

Assuming that antigen–antibody precipitates have lattice-like structures (see Figure 7 in the text), draw simple sketches showing possible arrangements of antigen and antibody molecules in a precipitate in which the ratio of antibodies to antigens is (a) 1.14 and (b) 2.83.

Question: Suppose that antibody is prepared against the extracellular portion of a particular hormone receptor known to have intracellular tyrosine kinase activity, and known to carry out autophosphorylation of its tyrosine kinase. Suppose further that addition of this antibody to target cells elicits intracellular responses similar to those obtained by addition of hormone itself. Propose a mechanism by which addition of antibody may mimic the effects of adding hormone. (Hint: Fab fragments do not elicit the hormone-like response.)

Explanation / Answer

I ONLY need help with the question asked at the bottom. Thank you. Students of b

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