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2. A 32-year-old man had been in excellent health until he was seen at a nearby

ID: 264144 • Letter: 2

Question

2. A 32-year-old man had been in excellent health until he was seen at a nearby clinic and was prescribed penicillin for a mild sore throat. He was able to return work and felt better. After several days, he developed a fever and experienced easy bruising. He noticed other bleeding symptoms including gingival bleeding and petechiae. He reported to the emergency room. A complete blood count (CBC) revealed abnormal results. He was admitted to the hospital for further evaluation. On admission, the CBC shows the following results with 3 selected abnormal cells shown below: Hb 8.3 g/dL RBC 2.45 x 10/L Plt 19 x 10 L WBC 2.3 x 10°/L Blasts Promyelocytes 82% Myelocytes Neutrophil Lymphocyte Monocyte 2% 490 3% 890 190 Peripheral blood In view of the large numbers of immature cells in the peripheral blood, bone marrow (BM) examination was requested. The BM was hypercellular with 4% blasts and 84% promyelocytes plus other nucleated cells Bone marrow

Explanation / Answer

2. A 32-year-old man had been in excellent health until he was seen at a nearby