1) How would a missense mutation in the start codon of the orf in the trp leader
ID: 263692 • Letter: 1
Question
1) How would a missense mutation in the start codon of the orf in the trp leader sequence affect expression of the trp operon?2) Mutations exist in the Trp Repressor gene that result in constitutive repression of the trp operon? Discuss how these mutations change the chemistry of the Trp Repressor.
3) The -10 core promoter of the lac operon gene has the sequence TATGTT. Describe an example of a base substitution mutation which would lead to increase transcription of the gene. Explain whether this mutation would increase or decrease the fitness of the organisms.
1) How would a missense mutation in the start codon of the orf in the trp leader sequence affect expression of the trp operon?
2) Mutations exist in the Trp Repressor gene that result in constitutive repression of the trp operon? Discuss how these mutations change the chemistry of the Trp Repressor.
3) The -10 core promoter of the lac operon gene has the sequence TATGTT. Describe an example of a base substitution mutation which would lead to increase transcription of the gene. Explain whether this mutation would increase or decrease the fitness of the organisms.
1) How would a missense mutation in the start codon of the orf in the trp leader sequence affect expression of the trp operon?
2) Mutations exist in the Trp Repressor gene that result in constitutive repression of the trp operon? Discuss how these mutations change the chemistry of the Trp Repressor.
3) The -10 core promoter of the lac operon gene has the sequence TATGTT. Describe an example of a base substitution mutation which would lead to increase transcription of the gene. Explain whether this mutation would increase or decrease the fitness of the organisms.
Explanation / Answer
1) How would a missense mutation in the start codon of the orf in the trp leader
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