The graphs below illustrate the uptake of D-glucose in the presence and absence
ID: 263397 • Letter: T
Question
The graphs below illustrate the uptake of D-glucose in the presence and absence of inhibitors. The inhibitors are simply named "Inhibitor 11" or "Inhibitor 12." Based on the data shown, describe the Vmax, KM and type of inhibition for each. The Vmax and K, should be determined in the presence and absence of each inhibitor. What do these data tell you about the function of a glucose transporter? (Data From: Ulanovskaya OA, Cui J, Kron SJ, Kozmin, SA (2011) A pairwise chemical genetic screen identifies new inhibitors of glucose transport. Chemistry & Biology, 18, 222-230.) 15 Inhibitor 12 12 Inhibitor 11 No Inhibitor No Inhibitor 10 -5 0 5 10 15 20 105 10 15 20 1/[D-Glucosel (mM) 1/[D-Glucose] (mM)Explanation / Answer
The graphs below illustrate the uptake of D-glucose in the presence and absence
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