A wild-type yeast strain is crossed with another strain that requires both argin

Question

A wild-type yeast strain is crossed with another strain that requires both arginine and uracil added to the medium to grow. The resulting cells undergo meiosis and the products of meiosis are analysed. There are three classes of unordered tetrads observed; the results are summarized below. What is the map distance between the arg and uracil genes?

Class 1 (125 tetrads):

2 spores grow on arg & uracil

2 wild-type spores

Class 2 (5 tetrads):

2 spores grow on arg

2 spores grow on uracil

Class 3 (70 tetrads):

1 wild-type spore

1 spore grows on arg & uracil

1 spore grows on arg

1 spore grows on uracil

Explanation / Answer

A wild-type yeast strain is crossed with another strain that requires both argin

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