Below is part of the DNA sequence for the funny gene with the corresponding prot

Question

Below is part of the DNA sequence for the funny gene with the corresponding protein sequence indicated above it. It has been found that a subset of canadians have a mutation in that gene and as a consequence, lack a sense of humor. The funny gene in these "lack a sense of humor" mutants was found to have an extra "A" nucleotide inserted within the funny gene as highlighted in yellow below. Stop codons should be entered as "." a) Complete the protein sequence (using the 1-letter code) for this mutated gene using the Table provided below. Do NOT add space or punctuation between amino acids. Stop codons should simply be entered as a period. Normal funny-gene: N'T HET IS VT. Q G C 5'- ACA CAT GAG AGA ACG ATA TCA GTA ACG AGG CAA GGT GA-3' "Lack a sense of humor" mutated gene: N'- -C' 5'- ACA CAT GAA GAG AAC GAT ATC AGT AAC GAG GCA AGG TGA-3' Submit Answer Tries 0/99 b) This type of mutation is called: Submit Answer Tries 0/99 Leu UC AG U Phe Ser Tyr Cys Phe Ser Tyr Cys Leu Ser STOP STOP Leu Ser STOP Trp Leu Pro His Arg Pro His Arg Leu Pro Gin Arg Leu lle Asn Ser Thr Asn Thr Lys Met Lys Val Ala Asp Val Ala Asp Val Glu Val Ala |_puu

Explanation / Answer

Q.A)

THEENDISNEAR.

Q.B)

It is known as frameshift mutation.

It is because a nucleotide (adenine) is added to the 9th postion of sequence as a result of which the reading frame of the sequence is completely changed.

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