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label each of the carbons in the following metabolites indicating whether, in hu

ID: 262558 • Letter: L

Question

label each of the carbons in the following metabolites indicating whether, in humans, they can end up being transferred to glucose via gluconeogenesis or whether they can only be transferred to acetyl-CoA

(1) Label each of the carbons in the following metabolites (images from Wikipedia and Pubchem') indicating whether, in humans, they can end up being transferred (in the net) to glucose via gluconeogenesis (gluconeogenic) or whether they can only be (in the net) transferred to acetyl-CoA (ketogenic) -you can circle a group of carbons and label the group, so long as it's obvious which carbons you label as gluconeogenic and which you label as ketogenic (do not worry about carbons in a CoA group). Calculate the net ATP yield from the complete, oxidative catabolism (e.g. to CO2 and H20) of any one of these metabolites (if you choose to calculate this for a CoA thioester, do not worry about catabolism of the CoA part). You may assume that (3 or 4 carbon) gluconeogenic substrates are equivalent to pyruvate in terms of net ATP yield (10 points). bat or 4 carbon) gluconeogenic su (A) (Pentanoyl-CoA) ?? O-P O. ?? NH2 NH2 NH2

Explanation / Answer

Answer a.

Pantothenoyl CoA can be only be transferred to Acetyl CoA during the metabolism.

Answer b.

It is arginine amino acid and glucogeneic in nature. Hence it ends up in gluconeogenetic pathway.

Answer C.

This is valine amino acid and glucogeneic in nature.