Which of the following is TRUE about the tryptophan operon in E.coli ? The trp r

Question

Which of the following is TRUE about the tryptophan operon in E.coli?

The trp repressor binds to the operator and changes its conformation to prevent RNA polymerase binding.

Tryptophan interacts with the repressor protein to turn off the operon.

The trp repressor binds to the operator and changes its conformation to allow RNA polymerase binding.

Tryptophan interacts with the repressor protein to turn on the operon.

The trp repressor binds to the operator and changes its conformation to prevent RNA polymerase binding.

Tryptophan interacts with the repressor protein to turn off the operon.

The trp repressor binds to the operator and changes its conformation to allow RNA polymerase binding.

Tryptophan interacts with the repressor protein to turn on the operon.

Explanation / Answer

Tryptophan interacts with the repressor protein to turn off the operon.

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When the tryptophan is present, it binds to the trp repressor and causes a conformational change. This results in the binding of repressor to the operator region thereby preventing RNA polymerase from transcribing the gene, thereby turning off the operon.

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