Why is a mutated single copy of a tumor-suppressor gene expected to behave as a
ID: 261583 • Letter: W
Question
Why is a mutated single copy of a tumor-suppressor gene expected to behave as a recessive gene?
a.Recessive mutations are more difficult for DNA repair machinery to correct than dominant mutations, and are more likely to contribute to cancer progression.
b. Pedigrees of families with an inherited predisposition to cancer, like those with familial retinoblastoma, display autosomal recessive inheritance patterns.
c. If the mutated gene was dominant, it would be impossible to be transported to the offspring, since the organism that carries this gene would not survive because of cancer.
2. Choose the correct explanation of the apparent paradox that both hypermethylation and hypomethylation of DNA are often found in the same cancer cell.
d. Although both hypermethylation and hypomethylation of DNA can occur in the same cancer cell, only hypermethylation results in cancerous changes.
3.
a. Although both hypermethylation and hypomethylation of DNA can occur in the same cancer cell, only hypomethylation results in cancerous changes. b. Complex regulatory systems are involved. For example, hypermethylation of oncogenes and hypomethylation of tumor-suppressor genes are expected in cancer cells. c. Complex regulatory systems are involved. For example, hypomethylation of oncogenes and hypermethylation of tumor-suppressor genes are expected in cancer cells.d. Although both hypermethylation and hypomethylation of DNA can occur in the same cancer cell, only hypermethylation results in cancerous changes.
3.
Explanation / Answer
1. The correct answer is c.
if the mutated gene was dominent, it would be impossible to be transported to the offspring, since the organism that carries this gene would not survive because of cancer.
2. The correct answer is B.
complex regulatory systems are involved. for example, hypermethylation of oncogenes and hypomethylation of tumor supressor genes are expected in cancer cells.
Related Questions
drjack9650@gmail.com
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.