A population of fruit flies is polymorphi for two alleles, A1 and A2. One thousa

Question

A population of fruit flies is polymorphi for two alleles, A1 and A2. One thousand populations are derived, and each is maintained by selecting at random 10 females and 10 males in each generation as parents of the following generation. After many generations, it is observed that 220 populations are fixed for allele A1, and 780 are fixed for allele A2.

a.) Estimate the allele frequencies in the original poplulation, assuming that only genetic drift is involved.

b.) Assuming that the initial fruit fly population from which the first parent were seleced was large and randomly breeding, calculate the frequencies for the genotypes A1A1, A2A2, and A1A2 in the initial population.

Explanation / Answer

As the population is large and random mating, and the frequencies of populations of A1 and A2 with only genetic drift is operating is Diversifying selection. And the allelic frequencies are equal ie., p+q=1 and p=q that is p=0.5 and q=0.5 Assuming that the initial population from which the first parent were selected was large and randomly breeding, frequencies of genotypes A1A1. A2A2 and A1A2 will be 25%, 25% and 50%

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