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Multiple Choice: Which of the follow statements is false? A. K63 polyubiquitinat

ID: 260449 • Letter: M

Question

Multiple Choice: Which of the follow statements is false? A. K63 polyubiquitination leads to downstream cellular signaling. B. K48 polyubiquitination leads to degradation by the proteasome. C. Out of the three families of enzymes involved in ubiquitination-E1 (ubiquitin-activating) enzymes, E2 (ubiquitin-conjugating) enzymes, and E3 enzymes (ubiquitin ligases)-Cbl is an E3 enzyme that selects its target via its 7.8 SH2 domain. D. Mono- or di-ubiquitination of surface receptors leads to degradation by the proteasome. Matching: Match the human disease with the gene that is defective: 7.9 A. X-linked i. ORAl1 agammaglobulinemia ?._Wiscott-Aldrich ii. NEMO syndrome C. Severe C.Severe combined ii. Btk immunodeficiency D. X-linked hypohidrotic iv. WASp ectodermal dysplasia and immunodeficiency 7.10 Fill-in-the-Blanks: Name the corresponding receptor or signaling comnonent in its resnective T/B cell o

Explanation / Answer

Answer:

1) Which of the following statement is FALSE?

2) Match the human disease with the gene that is defective: