Which of the following statements about DNA polymerase III holoenzyme from E. co
ID: 260007 • Letter: W
Question
Which of the following statements about DNA polymerase III holoenzyme from E. coli are correct?
A) It elongates a growing DNA chain hundreds of times faster than does DNA polymerase I
B) It associates with the parental template, adds a few nucleotides to the growing chain, and then dissociates before initiating another synthesis cycle.
C) It maintains a high fidelity of replication, in part, by acting in conjunction with a subunit containing a 3’ ? 5’ exonuclease activity.
D) When replicating DNA, it is a molecular assembly composed of at least 10 different kinds of subunits
Explanation / Answer
I believe the correct answer to be :
C) It maintains a high fidelity of replication, in part, by acting in conjunction with a subunit containing a 3’ - 5’ exonuclease activity.
It is the ? subunit that has this activity and is present in a holoenzyme.
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