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doc Other homework problems 3. Consider the following population genetic model i

ID: 259349 • Letter: D

Question

doc Other homework problems 3. Consider the following population genetic model in which the absolute fitnesses are: Aa and the frequency of the A allele is 0.8. Calculate the frequency of the A allele in the next generation. 4. Albinism is due to a recessive, autosomal mutation. The frequency of albino squirrels is 4 x 104, while heteruzygous squirrels, which are tan colored (and are lighter than wild-type squirreis), occur at frequency 0.004. Assume the population in at mutation-selection balance. a. What is the frequency of the albino allele? Show work. b. If the mutation rate to new albino alleles is 10t, what is the reduction af fitness of the heterozygote? 5. Assume that in a one locus, two-allele system, the frequency of the A allele is p and the population is in Hardy-Welnberg equilibrium Now, assume we catch a single random female, randomly collect two eggs from ber, and determine the genotype of each of these eggs What is the probability that we will get two eggs carrying the A allele? Express the answer in terms of p.

Explanation / Answer

Answer 3:

Frequency of A allele in next generation will remain same as in first generation that is 0.84

As acc. to THE HARDY-WEINBERG LAW

p2 + 2pq + q2 = 1

and p + q = 1

p (A)= frequency of the dominant allele in the population

q (a)= frequency of the recessive allele in the population

p2 = percentage of homozygous dominant individuals

q2 = percentage of homozygous recessive individuals

2pq = percentage of heterozygous individuals

q = 1- 0.8 = 0.2

for f generation = p2 + 2pq + q2

= .64 + 0.32 + 0.4

p for next generation = p2 + (p2 x 2pq )

P = 0.64 + 0.2048

Frequency of allele A in next generation (F1) = 0.8448