A disease displays variable expressivity but NOT incomplete penetrance. This mea
ID: 259181 • Letter: A
Question
A disease displays variable expressivity but NOT incomplete penetrance. This means that:
the disease may skip a generation
whoever has the abnormal allele, will display the phenotype to some degrees
the disease symptoms will appear later in life
the disease will be mildly expressed in some individuals
both homozygous recessive and heterozygous individuals will display the symptoms
B and D
D and E
Dentinogenesis imperfecta is an autosomal dominant disorder with 90% penetrance. Hemophilia is an X-linked recessive disorder. John has hemophilia. Sue has Dentinogenesis imperfecta, and is pregnant with a girl. What is the chance that their daughter will be unaffected for both conditions? Both of the traits are rare in the corresponding population.
Zero
30%
45%
50%
55%
A.the disease may skip a generation
B.whoever has the abnormal allele, will display the phenotype to some degrees
C.the disease symptoms will appear later in life
D.the disease will be mildly expressed in some individuals
E.both homozygous recessive and heterozygous individuals will display the symptoms
F.B and D
G.D and E
Explanation / Answer
I believe the correct option to be:
Answer 1) F) B and D
Answer 2) A) Zero
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