Answer the next two questions based on the following information. You are studyi

Question

Answer the next two questions based on the following information. You are studying two genes, gene 1 and gene 2. Gene 1 is normally off but is turned on in the presence of progesterone. Gene 2 is constitutively expressed. You "swap" the promoter regions for these two genes so that the promoter from gene 1 replaces the promoter from gene 2 and visa versa. What pattern of expression do you expect to see for the hybrid version of the gene containing the gene 1 coding region? Normally off but is turned on in the presence of progesterone Constitutively expressed Not expressed under any conditions because the gene 2 enhancer is unlikely to work in combination with the gene 1 promoter Not expressed under any conditions because the gene 1 enhancer is unlikely to work in combination with the gene 2 promoter Constitutively expressed but also expressed at a higher level in the presence of progesterone Submit Answer Tries 0/99 What pattern of expression do you expect to see for the hybrid version of the gene containing the gene 2 coding region? Constitutively expressed Not expressed under any conditions because the gene 1 enhancer is unlikely to work in combination with the gene 2 promoter Normally off but is turned on in the presence of progesterone Not expressed under any conditions because the gene 2 enhancer is unlikely to work in combination with the gene 1 promoter Constitutively expressed but also expressed at a higher level in the presence of progesterone

Explanation / Answer

The pattern of expression of the hybrid version of the gene containing the gene 1 coding region will be normally off but is turned on in the presence of progesterone

Because there are transcription factors which are responsible for the constitutive expression. These transcription factor are absent in this hybrid gene, therefore the expression will normally normally off but is turned on in the presence of progesterone

A promoter region is a particular DNA sequence within a DNA strand that acts as a signal for where RNA transcription should begin. It includes the binding site for RNA polymerase, the transcription start site, and sites where proteins that are responsible for regulating gene expression can bind.

The pattern of expression of the hybrid version of the gene containing the gene 2 coding region will be Constitutively expressed

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