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2. Fill in the blanks using the word list below a. The apolipoproteinis used to

ID: 257700 • Letter: 2

Question

2. Fill in the blanks using the word list below a. The apolipoproteinis used to dissolve lipids synthesized in the liver b. Muscle can use glucose , and fatty acids to support ATP production during vigorous exercise c. Glucagon signaling in adipose tisstue produces cAMP inducing the phosphorylation activating of lipases remo transported in the blood stream to muscle or liver by oxidation which releases ving free fatty acids from triglycerides. The free fatty acids are then for beta- d. Familial hypercholesterolemia is chatacterized by the development of which is associated with increased LDL clearance by and the subsequent deposition of dead foam cells in a blood vessel formation is required for the solubilization and transport of e. and cholesterol produced in the liver f in blood vessels releasing frece ApoC-? is required to activate fatty acids from lipoprotein particles. WORD LIST: lipases, perilipin, VLDL. ApoB-100, phosphocreatine, triacylglycerol. CGI protein, ketone bodies, atherosclerosis, macrophages, albumin

Explanation / Answer

The apolipoprotein ApoB-100 is used to dissolve lipids synthesis in the liver

Muscles can use glucose phosphocreatine and fatty acid to support ATP production during vigorous exercise.

Glucagon signaling in adipose tissue produces cAMP inducing the phosphorylation of perilipin Which releases CGI protein activating lipases removing free fatty acid from triglycerides.

The free fatty acids are then transported in the blood stream to muscle or liver by ketone bodies beta oxidation

Familial hypercholesterolemia is characterized by the development of atherosclerosis which is associated with increased LDL clearance by macrophages and the subsequent deposition of the dead foam cells in a blood vessel.

VLDL formation is required for the solubilization and transport of triglycerol and cholesterol produced in the liver.

ApoC-II is required to activate Lipase in blood vessels releasing free fatty acids from lipoprotein particles.

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