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11. Circle the CORRECT statement about glucagon signaling in the liver and the a

ID: 257687 • Letter: 1

Question

11. Circle the CORRECT statement about glucagon signaling in the liver and the activation of glycogenolysis a. Involves the production of cAMP, a secondary messenger required to stumulate PKA and the phosphorylation of phosphorylase kinase Inhibits the activation of G-protein alpha b. Gooole pcreases the levels of fructose-2,6-biphosphate .d.tooperates with insulin to stimulate gluconeogenesis e. Signals to the liver after a meal (fed conditions). 12. Hypercholesterolemia and atherosclerosis can be treated with inhibitors for cholesterogenesis. True or False 13. Which statement concerning glyceroneogenesis is INCORRECT a. Required to provide glycerol for triglyceride biosynthesis in liver b. Can supply up to 65% of the glycerol required for production of triglycerides c. Involves PEPCK and PC d. Is required to maintain free fatty acids at a high coucentration in the blood stream e Can be a targeted for the treatment of insulin resistance by thiazolinedioues in adipose tissue

Explanation / Answer

Ans. 11 (a) Breakdown of glycogen into glucose is called glycogenolysis. So glucagon hormone perform this pathway and lead to generation of CAMP then activate PKA and then phosphorylase kinase.

Ans. 12 true.

Ans. 13(