The following is a diagram of the trp operon which codes for genes that are part
ID: 257377 • Letter: T
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The following is a diagram of the trp operon which codes for genes that are part of a bacterial biosynthetic pathway that is used to make tryptophan. The genes within the operon are expressed only when tryptophan is absent from the environment. When tryptophan is present, trpR is bound to the operator and the biosynthetic genes are repressed. Based on the diagram, match the phenotype with the gene mutant. Operon trpR P O trpE trpD trpC trpB trpA trpE trpD trpC trpA trpB Biosynthetic yceCRPpptptophan anthranilic phosphoribosyl- anthranilate chorismic indoleglycerol phosphate Pathway acid acid tryptophan Choose...+ This mutation will lead to biosynthesis of tryptophan when tryptophan is present This mutation will lead to accumulation of phosphoribosylanthranilate when tryptophan is absent This mutation will prevent expression of any genes in the trp operon either in the presence or absence of tryptophan Choose....* This mutation will lead to accumulation of CDRP when tryptophan is absent This mutation will lead to accumulation of anthranilic acid when tryptophan is absent This mutation will lead to accumulation of chorismic acid when tryptophan is absent This mutation will lead to accumulation of indoleglycerol phosphate when tryptophan is absent Choose # Choose...+ Choose... + Choose Choose... +Explanation / Answer
The mutation will lead to accumulation of indoleglycerol phosphate when tryptophan is absent: trpB
The mutation will lead to accumulation of chorismic acid when tryptophan is absent: trpE
The mutation will lead to accumulation of anthralinic acid when tryptophan is absent: trp D
The mutation will lead to accumulation of CDRP when tryptophan is absent: trpA
The mutation will lead to accumulation of phosphoribosyl anthralinate when tryptophan is absent: trp C
The mutation will lead to the biosynthesis of tryptophan when tryptophan is present: When tryptophan is present, these tryptophan repressor dimers bind to tryptophan, causing a change in the repressor conformation, allowing the repressor to bind to the operator. This prevents RNA polymerase from binding to and transcribing the operon, so tryptophan is not produced from its precursor. so either the repressor is mutated or the operator is mutated.
The mutation will prevent the expression of any genes in trp operon either in the presence or absence of trp: Promoter mutation will prevet the binding of RNA polymerase which is needed for transcription of any trp genes.
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